Nuclear magnetic resonance spectroscopy with single spin sensitivity

Nuclear magnetic resonance spectroscopy with single spin sensitivity

Nuclear magnetic resonance spectroscopy and magnetic resonance imaging at the ultimate sensitivity limit of single molecules or single nuclear spins requires fundamentally new detection strategies. The strong coupling regime, when interaction between sensor and sample spins dominates all other interactions, is one such strategy. In this regime, classically forbidden detection of completely unpo...

Plused Nuclear Magnetic Spin Resonance

THEORY: The physics behind NMR/MRI signal production lies in the physics of spin. This section will cover enough aspects of spin to understand the generation of NMR signals. Although this initial spin discussion is inherently quantum mechanical in nature, we will later need to employ some simple principles from thermodynamics and classical dynamics to further describe the art of NMR. These topi...

Proton Nuclear Magnetic Resonance Spectroscopy

18. Nuclear Magnetic Resonance Spectroscopy

Nuclear Magnetic Resonance (NMR) is a spectroscopic technique widely used by organic chemists. NMR provides details about the location, number and environment of specific types of atoms within a sample. The proper interpretation of this information allows detailed chemical structures to be discerned. The same basic instrumentation used in this week’s experiment is used in physician offices when...

Pulsed Spin Decoupling in Nuclear Magnetic Resonance

group. The spectra, as shown in Figure 2 , can be semiquantitatively reproduced using the LAOCOON computer program with reduced values for the carbon-proton coupling constant^.^ These calculations are approximate because they do not include the asymmetry introduced by the decoupling field or any relaxation effects. We have performed additional experiments which show that it is not necessary for...